LaserToF TT

MALDI ToF/ToF MS/MS

LaserToF TT is a Research Grade MALDI-MS/ MS instrument, incorporating some of the most advanced performance and design features of any mass spectrometer.

The TT is the result of an accumulated knowledge base. It offers rapid and accurate single scan seamless MS/MS analysis. The design combines high resolution peptide mass fingerprinting and peptide sequencing by uni or bi molecular fragmentation. The instrument is equipped with a 2D sample stage (including 96/384/1536-well format) for high throughput automated analysis.

 

Key Features

  • Attomole Sensitivity
  • Novel "ZOOM" Lens
  • Outstanding Resolution
  • Collision Cell (CID)
  • Post Source Decay (PSD)
  • Ideal field Reflectron
  • Full Proteomics Software
  • Mass Spectrometer
  • Time of Flight Mass Analyser:
  • Novel Ideal Field reflectron design enabling seamless MS/MS in a single scan
  • Unique 2-D sample stage with fast change over and precise positioning
  • Integrated sample viewing camera and laser optics to give maximum control of experiments
  • Advanced acquisition and control electronics capable of operation with high repetition laser frequencies
  • High stability and automatic calibration for maximum precision in peptide measurements
  • Detector:
  • Long lifetime low maintenance fast electron multiplier detection system as standard for linear operation
  • Fast hybrid multiplier detector as standard for reflectron operation giving high gain, large dynamic and linear range for improved system performance
  • Data System
  • Hardware:

Integrated personal computer based on a Pentium processor and including:

  • 512 Mbytes of RAM
  • 80 Gbyte hard disk drive
  • CD-ROM drive
  • High resolution colour monitor.
  • Network connection

Software:

  • Full control of all MS parameters
  • Data acquisition and data reduction program
  • Automated sequence programming for batch operation
  • Integrated camera and viewing software
  • Report generator and Open Office
  • Database search of both peptide map and PSD data
  • The system comes network ready

Specifications:

  • Resolution: Reflectron >20,000 (FWHM)
  • ACTH(MH+2465)
  • Linear >4,000 (FWHM)
  • ACTH(MH+2465)
  • Mass Accuracy External calibration
  • 100ppm RMS
  • Mass Accuracy Internal calibration
  • <5ppm RMS
  • Precursor Ion Selection 100 (FWHM)
  • PSD Resolution > 5,000 (FWHM)
  • Mass Range > 500,000 Da.
  • Sensitivity < 1fmol

Vacuum System:

Differential pumping provided by two high efficiency air cooled turbo - molecular pumps (250 l/s) coupled to a two stage rotary pump.
 

Services Required:

  • Power: 220-250V, 13 amps, single phase or 110V single phase
  • Environment: Temperature range 15-27°C
  • Dimensions: 65 x 85 x 220 cm (W x D x H)
  • Weight: 250 Kilos Approx 

 

AttachmentSize
In Vitro Proteomic Profile Analysis of Metastatic Prostate Cancer By MALDI-TOF-TOF MS.pdf36.6 KB
Zoom Optics for Optimised MALDI Sensitivity.pdf78.05 KB
Low Attomole Sensitivity with Optimised MALDI ToF Zoom Optics.pdf177.94 KB
LaserTof-TT product sheet.pdf695.38 KB

Want to know more?

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